DUTCH Adrenal

DUTCH Adrenal measures hormones associated with adrenal gland function using dried urine samples collected at multiple points throughout a single day. The test includes evaluation of the daily profile of free cortisol and cortisone, cortisol and cortisone metabolites, as well as DHEA-S, all analyzed using LC-MS/MS technology and normalized to creatinine.

These markers are included to provide a detailed, multi-level picture of adrenal hormone activity throughout the day. Free cortisol and cortisone profiles offer information about the daily rhythm and timing of hormone secretion, while metabolite measurements reflect total hormone production. DHEA-S adds additional information about longer-term adrenal hormone production, allowing for a more complete interpretation than single-marker testing.

Typically, specialists interpret DUTCH Adrenal results along with the patient's symptoms, sleep-wake rhythm, lifestyle factors, stress exposure levels, and other lab results. Results are analyzed in context to understand how daily hormone patterns correlate with each patient's individual experience and condition.

Recommended for:

Women:

• Fatigue or low energy levels: persistent tiredness or reduced endurance.
• Low mood or depression: changes in emotional state, motivation, or overall sense of well-being.
• Reduced libido: decreased sexual desire or interest.
• Premenstrual symptoms: premenstrual syndrome (PMS) or symptoms that occur cyclically in relation to menstruation.
• Menopausal transition: changes associated with menopause, such as sleep disturbances or hot flashes.
• Weight gain: gradual or unexplained increase in body weight.

Men:

• Fatigue or low energy levels: continuous tiredness or reduced energy and physical drive.
• Low mood or depression: persistent sadness, lack of motivation, or decreased interest in usual activities.
• Decreased sex drive: diminished libido or changes in sexual interest.
• Sleep disorders: difficulty falling asleep or staying asleep.
• Hair loss: thinning hair or changes in hair growth patterns.
• Weight gain: abdominal weight accumulation or general increase in body mass.